Bruce Hamilton,Christopher Herring,Mark Andrew Paulik,Hamilton, Bruce,Herring, Christopher,Paulik, Mark Andrew
申请号:
US13498924
公开号:
US20120276098A1
申请日:
2010.09.23
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to drug fusions and conjugates that have improved serum half lives. These fusions and conjugates comprise immunoglobulin (antibody) single variable domains and insulinotropic and/or incretin and/or gut peptide molecules. The invention further relates to uses, formulations, compositions and devices comprising such drug fusions and conjugates. The invention also relates to compositions which comprise more than one insulinotropic and/or incretin and/or gut peptide molecules present as part of a fusion or conjugate and to uses and formulations thereof.