Polina Olegovna Anikeeva,Alexander William Senko,Danijela Gregurec,Pooja D. Reddy
申请号:
US16427911
公开号:
US20200001104A1
申请日:
2019.05.31
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides novel methods and devices for the remote stimulation of mechanosensitive cells using magnetically-induced forces that are significantly lower in magnitude than currently possible. Novel biocompatible anisotropic magnetic nanodiscs allow for remote magnetomechanical stimulation of cell signaling in mechanosensitive cells at scale without compromising cell viability. The methods and devices of the present invention allow for investigation of mechanoreception in general, and in particular, for studies in neurological, neurodegenerative; and neuromuscular diseases.