METHODS OF CONTROLLING VASCULARITY USING RAVER2 AS A MEDIATOR FOR EXPRESSION OF VEGF RECEPTOR SFIT1

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专利权人:

发明人:

Balamurali K. AMBATI,Derick G. HOLT

申请号：

US14765226

公开号：

US20160263184A1

申请日:

2014.02.03

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Methods of treating a condition in a subject resulting from abnormally high VEGF signaling through membrane-bound receptors. Such a method can include increasing expression of Raver2 in affected cells of the subject to increase production of soluble VEGF receptors. In some aspects, increasing expression of Raver2 decreases production of membrane-bound VEGF receptors.

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