The present invention relates to thymosin ²4 (T²4) derivatives, Gly-T²4 and Ala-T²4. The present invention further relates to a pharmaceutical composition comprising the said T²4 derivatives. The present invention also relates to the use of said T²4 derivatives in manufacture of a medicament for treatment of skin lesion, heart injury, corneal lesion and/or coronary heart disease. The present invention further relates to a method of treatment for skin lesion, heart injury, corneal lesion and/or coronary heart disease by using the said T²4 derivatives.
