ASSOCIATION FOR THE ADVANCEMENT OF TISSUE ENGINEE RINGANDCELL BASED TECHNOLOGIES AND THERAPIES A4TEC
发明人:
Rui Luis GONÇALVES DOS REIS,Ana Rita CRUZ DUARTE,Alexandre António ANTUNES BARROS,Estêvão Augusto RODRIGUES DE LIMA,Carlos André RIBEIRO OLIVEIRA,Jorge Manuel NUNES CORREIA PINTO
申请号:
US15574046
公开号:
US20180296734A1
申请日:
2016.05.17
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Stents and methods for producing stents are provided. The stent includes a polymeric substrate comprised of 10-50% (w/w) of alginate and 45-85% (w/w) of gelatine and further includes a polymeric biodegradable resin for coating said polymeric substrate. The stent can also include a contrast agent. The stent can further include a crosslinking agent. The method for producing the stent includes dissolving the alginate and gelatine in water and stirring to obtain a polymeric substrate. The method also includes adding a crosslinking agent to the substrate, injecting the substrate into a mold to obtain the stent, placing the stent in a first alcohol solution, and placing the stent in a crosslinking agent solution. The method further includes placing the stent in a second alcohol solution, and a series of interchanging drying and immersing steps.