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TRANSPLANTATION OF HUMAN NEURAL CELLS FOR TREATMENT OF NEURODEGENERATIVE CONDITIONS
专利权人:
INC.;NEURALSTEM
发明人:
MARSALA, MARTIN,JOHE, KARL K,HAZEL, THOMAS G,KAKINOHAMA, OSAMU,KOLIATSOS, VASSILIS,YAN, JUN,REIER, PAUL J,VELARDO, MARGARET J
申请号:
PH12015501195
公开号:
PH12015501195A1
申请日:
2015.05.28
申请国别(地区):
PH
年份:
2015
代理人:
摘要:
A method of treating neurodegenerative conditions is provided. Neural stem cells may be implanted at and/or remote from a region of neuron degeneration. The methods can include isolating neural stem cells from regions where specific types of neurons corresponding to the neurons to be replaced are generated. The methods can include isolating neural stem cells secreting growth factors affecting the growth and/or regeneration of specific types of neuron. In this invention, we disclose a method of treating such disorders, including several neurodegenerative disorders arising from the lack of cells that produce particular neurotransmitters in neural circuitry by transplanting exogenously cultured and expanded neural progenitors which, upon transplantation into a neural tissue, differentiate into neurons capable of integrating and producing neurotransmitters in sufficient quantities and in a sufficient manner to overcome the symptoms associated with the neurodegeneration.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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