PROBLEM TO BE SOLVED: To provide a compound having excellent inhibitory action to pim-1 kinase and being useful for leukemia and prostate cancer, and an anticancer agent comprising the compound as an active ingredient.SOLUTION: A compound is represented by the formula (I) and an anticancer agent comprises the compound as an active ingredient. [In the formula, Ris H, OH, a Calkoxy group or the like； Rand Rare H, a halogen atom, a Calkyl group or the like； Ris H, a Calkyl group and a Calkylsulfonyl group； Ris H or a substituent group； ---- is a single bond or a double bond, Rand Rare H, a Calkyl group or the like； Ris H, a Calkyl group or the like； A is -O-, -S- or -CH-； D is -C= or -N=； X is a methylene group, -O- or -CO-； Q is -N= or -C(R)=； and Y is a heterocyclic group or an amino group.]【課題】pim-1キナーゼに対して優れた阻害作用を有し、白血病や前立腺癌に対して有用な化合物、及び該化合物を有効成分として含む抗癌剤の提供。【解決手段】式(Ｉ)で表される化合物、及び該化合物を有効成分として含む抗癌剤。［Ｒ1はＨ、ＯＨ、Ｃ1-6アルコキシ基等；Ｒ2及びＲ3はＨ、ハロゲン原子、Ｃ1-6アルキル基等；Ｒ4はＨ、Ｃ1-6アルキル基、Ｃ1-6アルキルスルホニル基等；Ｒ5はＨ又は置換基；----は単結合又は二重結合；Ｒ6及びＲ7はＨ、Ｃ1-6アルキル基等；Ｒ8はＨ、Ｃ1-6アルキル基等；Ａは-Ｏ-、-Ｓ-、又は-ＣＨ2-；Ｄは-Ｃ=又は-Ｎ=；Ｘはメチレン基、-Ｏ-、又は-ＣＯ-；Ｑは-Ｎ=又は-Ｃ(Ｒ8)=；Ｙはヘテロ環基又はアミノ基］【選択図】なし
