A two-stage teething mitten is provided that includes a fabric pocket defining an interior cavity adapted to enclose an infant hand. An opening is provided in the pocket to accommodate the insertion of an infant hand into the interior cavity. An elongate strap is positioned on the pocket adjacent the opening for detachably securing about the circumference of a wrist of the infant hand. A detachable teething member, which may take the form of a sleeve dimensioned to partially enclose the pocket, a teething ruff that may be attached to the elongate strap, or a second replacement fabric pocket, is provided.
