Richard G. Saul;Victor C. Esch;Sergey A. Dryga;Andrew F. McDowell
发明人:
Sergey A. Dryga,Victor C. Esch,Richard G. Saul,Andrew F. McDowell
申请号：
US12855147
公开号：
US09389225B2
申请日:
2010.08.12
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The invention generally relates to using magnetic particles and alternating magnet fields to separate a target analyte from a sample. In certain embodiments, methods of the invention involve contacting a sample with magnetic particles including first moieties specific for a target analyte, thereby forming target/particle complexes in the sample, flowing the sample through a channel including second moieties attached to at least one surface of the channel, applying alternating magnetic fields to the flowing sample to result in target/particle complexes being brought into proximity of the surface to bind the second moieties and unbound particles remaining free in the sample, binding the target/particle complexes to the second moieties, and washing away unbound particles and unbound analytes of the sample.
