Bone-targeting antibodies

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专利权人:

Genzyme Corporation

发明人:

Qiu, Huawei,Park, Sunghae,Stefano, James

申请号：

AU2018210270

公开号：

AU2018210270A1

申请日:

2018.01.19

申请国别(地区):

AU

年份:

2019

代理人:

摘要：

Provided are recombinant and chemically-conjugated antibodies and fragments thereof modified with one or more poly-aspartate (poly-D) peptides {e.g., a D10 sequence) to improve localization of the antibodies or fragments to bone. Methods of making and using of these antibodies and fragments also are disclosed.

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中国工程科技知识中心

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http://www.ckcest.cn/home/