L-丙氨酸-(14-冬淩草甲素)酯三氟乙酸鹽的I型結晶及製備方法

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专利权人:

发明人:

申请号：

HK16111954.3

公开号：

HK1223618B

申请日:

2016.10.17

申请国别(地区):

HK

年份:

2018

代理人:

摘要：

The present invention relates to an I-type crystal of L-alanine-(14-oridonin) ester trifluoroacetate and a preparation method therefor.The preparation method comprises crystallizing a L-alanine-(14-oridonin) ester trifluoroacetate solid in any crystal form or amorphous form in a single organic solvent or a mixed organic solvent thereof to obtain the I-type crystal of the L-alanine-(14-oridonin) ester trifluoroacetate.The I-type crystal of the L-alanine-(14-oridonin) ester trifluoroacetate obtained in the present invention has a good crystal form stability and chemical stability, and uses a crystallization solvent which has a low toxicity and low residue, and can be better used in clinical treatments.

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