This invention regards the medicine composition which possesses dissolved the lipophilic medicine to in water medium you improve. For example lipophilic chemical compound, such as hormone and steroid (, dorosupirenon and valeric acid esutorajioru) the powder of lipophilic including chemical compound, you discovered the medicine composition which becomes. The carrier which at least possesses the surface area of specification of 250 m2 /g (silicon dioxide and the like, for example Aeroperl (trade mark) silicon dioxide which are sold with trade name) with as for the molecular dispersion which becomes simultaneous, liquation characteristic of the lipophilic medicine was made to improve.本発明は、水性媒体中への親油性薬物の改善した溶解性を有する医薬組成物に関する。親油性化合物、ホルモン及びステロイド等(例えば、ドロスピレノン及び吉草酸エストラジオール)の親油性化合物のパウダーを含んで成る医薬組成物を見出した。少なくとも250 m2/gの特定の表面積を有する担体(二酸化ケイ素等、例えばAeroperl(商標)の商品名で販売されている二酸化ケイ素)と一緒になった分子分散は、親油性薬物の溶出特質を改善させた。
