#$%^&*AU2012203395A120120628.pdf#####ABSTRACT Chelating and binding chemicals to a medical implant, and therapeutic applications. Implantable 'metal chelated surface and chemical coated' medical implant device - drug (or biological moiety) coated or drug eluting stent, prosthesis, or other, 5 includes a medical implant component having metal surface (M) with chemical entity (X) bound via chelator (C) chelated to the metal surface in an (M) - (C) - (X) configuration. Chelator or/and chemical entity - drug (or biological moiety), linker bonded to a drug (or biological moiety), other, are bound at surface concentration greater than 100 picograms 2 per cm . Manufacturing the implantable medical device. Medical implant system 10 including medical implant component and delivery device for delivering and implanting medical implant component in a subject. Implanting the medical device. Preventing or/and treating medical conditions, such as restenosis or/and thrombosis, by implanting the medical device, wherein activity of bound chemical entity exhibits efficacy towards the medical condition. 15 3427761_1 (GHMatters) P75876.AU.11/4 CNJ >； $D E cq E CfCD K Ed 00 cn~ 0c c.~JC0 to
