The present invention is directed toward pharmaceutical compositions comprising an isolated polypeptide and a pharmaceutically acceptable carrier. The present invention also discloses an antibody or an antigen-binding portion thereof that bind to the isolated polypeptide. Methods of inhibiting cancer cells growth are also disclosed, comprising administering the isolated polypeptide or the antibody described herein to a subject in need thereof.本發明係關於包含經分離之多肽及醫藥學上可接受之載劑的醫藥組合物。本發明亦揭示結合於經分離之多肽的抗體或其抗原結合部分。亦揭示抑制癌細胞生長之方法,包含向有需要之個體投與本文所述之經分離之多肽或抗體。