The utility model relates to a medicine cutting box device, which comprises an upper cover part, a base part and a safety guard.Slice.The upper cover part includes a first joint part, a second joint part and a plurality of blade seats for holding a plurality of blades.The base part is connected with the upper cover part, including a second holding space, a first butt joint, a second butt joint, a first top back part, a second top back part and a plurality of fixed devices.The safety baffle includes a groove, a first butting part, a plurality of third holes and a plurality of fourth holes.Among them, the upper cover part and the base part can carry out a first action; the safety baffle is placed between the upper cover part and the base part.With the combination, the utility model can achieve the effect that multiple drugs can be cut and extracted without injury.一種切藥盒裝置,包括有一上蓋部、一基座部以及一安全檔片。該上蓋部包括有一第一接合部、一第二接合部、複數個刀片座容置複數個刀片。該基座部,與該上蓋部相連接,包括有一第二容置空間、一第一對接部、一第二對接部、一第一頂靠部以及一第二頂靠部以及複數個固定裝置。該安全檔片包括有一溝槽、一第一抵靠部、複數個第三孔洞以及複數個第四孔洞。其中,該上蓋部與該基座部可進行一第一動作;該安全檔片置放於該上蓋部與該基座部間。藉由上述組合可達成可將多顆藥物進行切割、提取藥物時不易受傷之功效。