There is provided an image registration device, method, and program that enable easy initial registration between a target object included in a video and a simulation image. A first registration unit performs first registration that is initial registration between an intraoperative video and a simulation image. At this time, a boundary image showing the boundary of the simulation image is displayed on a display so as to be superimposed on the intraoperative video. An operator performs registration between a target object included in the intraoperative video and the boundary image. After the end of the first registration, a second registration unit performs second registration between the simulation image and the target object included in the intraoperative video based on the result of the first registration.
