Sonia I. Maffioli,Paolo Monciardini,Bruno Catacchio,Mariacristina Brunati,Carlo Mazzetti
申请号：
US14648696
公开号：
US09975930B2
申请日:
2013.11.27
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention concerns novel antibiotic compounds, which are lantibiotics, the processes for their preparation, their pharmaceutically acceptable salts, pharmaceutical compositions containing the lantibiotics, and their use as antibacterial agents. Compounds designated as lantibiotics, such as those of the present invention, are peptides belonging to the general class of antibiotic compounds, and are further generally characterized by the presence of the amino acids lanthionine and/or 3-methyllanthionine. The novel lantibiotic compounds are active against bacterial infections caused by Clostridium difficile, Staphylococcus spp., Streptococcus spp, Enterococcus spp., and other bacteria.
