EFFECTIVE ANTIBACTERIAL HYDROPHILIC PHOSPHONIUM POLYMERS WITH LOW HEMOLYTIC ACTIVITY

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专利权人:

THE UNIVERSITY OF WESTERN ONTARIO

发明人:

CUTHBERT, Tyler J.,TRANT, John Frederick,GILLIES, Elizabeth Rachel,RAGOGNA, Paul Joseph

申请号：

WO2018CA50621

公开号：

WO2018213939(A1)

申请日:

2018.05.28

申请国别(地区):

世界知识产权组织国际局

年份:

2018

代理人:

摘要：

This disclosure provides phosphonium polymers with increased hydrophilicity exhibiting increased antibacterial activity and decreased hemolytic activity. These phosphonium polymers include Poly(THPvbPCl) poly(tris(3-hydroxypropyl)(vinylbenzyl)phosphonium chloride) and derivatives thereof, ((2,3,4,6-Tetra-O-acetyl-manno-pyranyl)-1-oxy-allyl and derivatives thereof, and poly(dihexyl(2,3,4,6,-hydroxy-gluco-pyranyl)-1-oxy-propyl)vinylbenzylphosphonium chloride) and derivatives thereof.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/