A patient monitoring system according to one embodiment includes a real-time wetness sensor configured to detect the rate of change in wetness occurring within an associated diaper, and automatically adjusting the sensitivity of the sensor to account for a wetness event unrelated to urination. A monitoring unit may be utilized in such a manner that the monitoring system controller-monitors the wetness sensor and generates data associated with detected-wetness events relative to the diaper. A wireless transmitter configured with the monitoring unit and in communication with the monitoring system controller may be further utilized to send the generated data, through a host computer, to a caregiver unit having a caregiver system controller in communication with the host computer. The caregiver can then check the status of the patient, provide a service, and annotate the patients history by transmitting the recorded observation and service provided back to the base station.