1H-Quinazoline-2,4-diones and their use as AMPA-receptor ligands

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专利权人:

NOVARTIS AG

发明人:

GUIBOURDENCHE, CHRISTEL,CARCACHE, DAVID,ORAIN, DAVID,ALLGEIER, HANS,MATTES, HENRI,NOZULAK, JOACHIM,RENAUD, JOHANNE,KALLEN, JORG,KOLLER, MANUEL,FLOERSHEIM, PHILIPP,FROESTL, WOLFGANG,AUBERSON, YVES

申请号：

AU2011200888

公开号：

AU2011200888B2

申请日:

2011.02.28

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

C nN rbrDCC AVK n07709_1.DOC-16/,201W The present invention relates to I H-Quinazoline-2,4-diones of formula (I) wherein R' and R2 are as defined in the specification, their preparation, their use as AMPA-receptor ligands, in particular for the treatment of epilepsy or schizophrenia, and pharmaceutical compositions containing them. Further, intermediates for the manufacture of compounds of formula (1) and combinations comprising compounds of formula (I) are disclosed.

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