David Edward Watson,Robert W. Siegel,Nan Jia,John Harrison Sloan
申请号:
US14361017
公开号:
US09453073B2
申请日:
2012.11.27
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Provided are monoclonal antibodies, or antigen-binding fragments thereof, that bind to glucagon. These antibodies are useful in immunoassays of glucagon levels, and/or in vivo, ex vivo or in vitro immunochemical and other imaging methods for detecting glucagon levels, and for diagnostic, prognostic and predictive purposes, and for optimizing therapeutic regimens in patients in which glucagon signaling is implicated in pathogenesis.