Tice, Colin M.,Michelotti, Enrique L.,Hormann, Robert E.
申请号：
AU2011226966
公开号：
AU2011226966B9
申请日:
2011.09.30
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
#$%^&*AU2011226966B920121004.pdf#####ABSTRACT This invention relates to a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain； a ligand binding domain； a transactivation domain； and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element； wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene. The ligands comprise a class of ketones. CVBE 6X EcRE Reporter P/00/008b C: NRPonb DCC KZL 2992318_1 DOC - 216/10
