The invention relates to a composition for the treatment of skin lesions and/or nail lesions, an applicator comprising such a composition and the use of such a composition. The composition comprises an effective amount of trichloroacetic acid and/or salicylic acid, at least one thickener, and at a physiologically acceptable solvent. And is effective against a plethora of skin lesions, in particular warts, corn and calluses, as well as nail lesions including ingrown toenails and onchyomycosis.