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Blood-brain barrier transmigrating compounds and uses thereof
专利权人:
National Research Council of Canada
发明人:
Chakravarthy, Balu,Stanimirovic, Danica,Durocher, Yves
申请号:
AU2018212860
公开号:
AU2018212860A1
申请日:
2018.01.30
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
A brain-penetrating composition of amyloid-ß binding peptide is disclosed. This may be useful in the treatment of Alzheimer's disease, for example as a bifunctional molecule, comprising a blood-brain barrier crossing antibody and an amyloid-ß targeting peptide linked via an Fc fragment that is able to transmigrate across the blood-brain barrier into the brain, and compositions comprising same. Methods of using this composition for treating Alzheimer's disease are disclosed.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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