Freeman, Donald Barclay,Benedict, James J.,Brewster, Greg Allen
申请号：
AU2006326020
公开号：
AU2006326020B2
申请日:
2006.12.15
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
A firm but pliable medical device for use as a bone graft substitute or bone graftextender retains its shape without the requirement of a containment device,such as a syringe. Because the device is solid, it is easy to locate or positionin-vivo and, in the moist environment of the body, it will hold its shape well,for an extended time. Because the lyophilized pliable medical device is porous,it adsorbs blood and other beneficial cells containing body fluids, such as bonemarrow, contributing to its superior bone repair efficacy in comparison to ananalogous putty that has not been lyophilized. In addition these lyophilizedpliable medical devices are easier to terminally steam sterilize than the analogousputty because there is no moisture present to boil and "blow-out"of the containment device (syringe). The glycerin that is present in the formulationlends pliability but has a low vapor pressure.
