Computerized information processing methods for processing data from a medical device, such as an ingestible probe. In one embodiment, the method includes processing data obtained by the probe so as to produce a plurality of image frames, and further processing the frames to identify a plurality of frames of potential interest to a reviewer based on at least an evaluation of portions of the frame(s) such as pixels or groups of pixels, and using the identified frames to form a preview of the entire data set. In one implementation, the processing of the data includes processing of pixel intensity and/or color (which can be correlated to various physiologic conditions) to help identify the frames of potential interest.