Manual use device (10) suitable for carrying out human tissue treatments with ultrasound to eliminate localized fat, cellulite, etc., where the manual use device (10) consists of at least one ultrasonic transducer (15, 16) and an element (20) for holding the manual use device (10) itself; where said manual use device (10) consists of: - A box-shaped body (11) that has a concave element as a depression (13) whose contour (CNT), during use, rests on the skin to be treated; - Two ultrasound transducers (15, 16) placed on the walls of said concave element (13), where said ultrasound transducers (15, 16) are inclined with respect to each other at an angle (α); wherein, between said two ultrasound transducers (15, 16), there is a suction mouth (14) connected to electropneumatic means, said suction mouth (14) being suitable for raising a tissue fold, such that the two adjacent portions of tissue, in which sa has preferably extended oil or gel, are brought into contact with the ultrasound transducers (15, 16); manual use device (10) characterized in that the relative angle (α) of said two ultrasound transducers (15, 16) varies between 0 ° and 180 °, using electromechanical means, according to the thickness of the fat layer and / or the part of the human body that is going to be treated.Dispositivo de uso manual (10) adecuado para llevar a cabo tratamientos de tejido humano con ultrasonidos para eliminar adiposidad localizada, celulitis, etc., donde el dispositivo de uso manual (10) consta de al menos un transductor de ultrasonidos (15, 16) y un elemento (20) para sujetar el propio dispositivo de uso manual (10); donde dicho dispositivo de uso manual (10) consta de: - Un cuerpo en forma de caja (11) que presenta un elemento cóncavo a modo de depresión (13) cuyo contorno (CNT), durante su uso, se apoya sobre la piel a ser tratada; - Dos transductores de ultrasonidos (15, 16) colocados sobre las paredes de dicho elemento cóncavo (13), donde dichos transductores de ultrasonidos