PROBLEM TO BE SOLVED: To provide a therapeutic agent for the growth inhibition and recurrence metastasis inhibition of gastric cancer which expresses MET, esophageal cancer, colon cancer, lung cancer, breast cancer, hepatoma, renal cancer, pancreatic cancer, and ovarian cancer.SOLUTION: The multi-kinase inhibitor, anticancer agent, anti-metastasis agent, drug resistance inhibitor, pain inhibitor and antipruritic agent contain a flavonol or a glycoside thereof which has general formula 1, such as herbacetin or gossypetin, as an active ingredient.COPYRIGHT: (C)2014,JPO&INPIT【課題】METを発現する胃癌、食道癌、大腸癌、肺癌、乳癌、肝癌、腎癌、膵臓癌、及び卵巣癌の増殖抑制及び再発転移抑制のための治療剤の提供。【解決手段】ヘルバセチンやゴシペチンなどの、式1を備えるフラボノールまたはその配糖体を有効成分として含有するマルチキナーゼ阻害剤、抗癌剤、抗転移剤、薬剤耐性抑制剤、疼痛抑制剤及び止痒薬。【選択図】なし