Discovery of regulatory T cells programmed to suppress an immune response

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专利权人:

Inc.;Dana-Farber Cancer Institute

发明人:

Cantor, Harvey,Kim, Hye-Jung,Lu, Linrong

申请号：

AU2011317211

公开号：

AU2011317211A1

申请日:

2011.10.18

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

A method to treat an autoimmune disease is provided. The method involves administration of interleukin-15 receptor (IL-15R) agonists in an amount effective to ameliorate a symptom of the autoimmune disease. The invention also involves a method to treat an autoimmune disease by ex- vivo expansion of CD44+CD122+Kir+ CD8+ Treg cells and administration of the CD44+CD122+Kir+ CD8+ Treg cells. Compositions comprising CD44+CD122+Kir+ CD8+ Treg cells are also provided. Methods for stimulating an immune response to an antigen are also provided.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/