aprotinin-derived polypeptide-antibody conjugates abstract: the present invention relates to protein conjugates comprising an aprotinin-derived polypeptide, which facilitates transport of the conjugate across the blood-brain barrier, and an antibody moiety that selectively binds to target within the cns. the protein conjugates are further defined by the inclusion of a linker； by the number of polypeptides conjugated to each antibody moiety； by the positions at which the antibody moiety and the polypeptides are conjugated； and by the larger configuration of the conjugate (in which every polypeptide is linked only to the antibody moiety). modified aprotinin-derived polypeptides, linker-bound antibody moieties, pharmaceutical compositions, kits, and methods of making and using protein conjugates are also features of the invention. patent abstract: "aprotinin-derived polypeptide antibody conjugates". The present invention relates to protein conjugates comprising an aprotinin-derived polypeptide, which facilitates transport of the conjugate across the blood-brain barrier, and an antibody component that selectively binds to a target within the cns. protein conjugates are further defined by the inclusion of a binder； by the number of conjugated polypeptides in each antibody component； at the positions at which the antibody component and polypeptides are conjugated； and by the larger conjugate configuration (wherein each polypeptide is bound to the antibody component only). modified aprotinin-derived polypeptides, ligand-bound antibody components, pharmaceutical compositions, kits, and methods of producing and using protein conjugates are also aspects of the invention. 1/1aprotinin-derived polypeptide-antibody conjugates abstract: the present invention relates to protein conjugates comprising an aprotinin-derived polypeptide, which facilitates transport of the conjugate across the blood-brain barrier, and an antibody moiety that selectively binds a target within the cns. th
