Tetracyclic compounds produced by monocyclic and bicyclic carboxylic acids; cycloenzyme activators; pharmacological synthesis; useful substances for the treatment of cardiovascular and inflammatory diseases as well as liver, skin, kidney, lung and heart diseases, such as kidney disease and diabetes, Glaucoma, poliomyelitis, urinary disorders including bladder hypertension, benign proton hyperplasia, etc.
SARKO CHRISTOPHER RONALD,YU MAOLIN,BRENNEMAN JEHROD BURNETT,GINN JOHN DAVID,WESTBROOK JOHN,ZHANG ZHONGHUA,HOPKINS TAMARA DENISE,LOWE MICHAEL D.
申请号:
CL2017000071
公开号:
CL2017000071A1
申请日:
2017.01.11
申请国别(地区):
CL
年份:
2017
代理人:
摘要:
Tetracyclic compounds produced by monocyclic and bicyclic carboxylic acids; cycloenzyme activators; pharmacological synthesis; useful substances for the treatment of cardiovascular and inflammatory diseases as well as liver, skin, kidney, lung and heart diseases, such as kidney disease and diabetes, Glaucoma, poliomyelitis, urinary disorders including bladder hypertension, benign proton hyperplasia, etc.Compuestos tetracíclicos derivados de un ácido carboxílico mono y bicíclico, activadores de guanilato ciclasa (sGC); composiciones farmacológicas; útiles para el tratamiento de enfermedades cardiovasculares e inflamatorias y a trastornos fibróticos hepáticos, dérmico, renales, pulmonares y cardiacos, tales como enfermedad renal, diabetes, glaucoma, distrofia, trastornos urológicos que incluyen hiperactividad de la vejiga, hiperplasia benigna protática, entre otras.