D. Olin Beck,Daniel T. Garner,Jeffery V. Gubler,Dennis J. Blume
申请号：
US13718310
公开号：
US20140170593A1
申请日:
2012.12.18
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Adhesive patches for non-invasive pain relief comprising a molded backing layer including first and second well portions. An adhesive composition (e.g., chitosan derived) is disposed within the first well composition, and a skin penetrating anesthetic composition is disposed within the second well portion. The first well portion surrounds the perimeter of the second well portion, creating a barrier to prevent or minimize migration of the anesthetic composition outside the perimeter of the second well portion, targeting delivery to the desired site. The skin penetrating anesthetic composition includes a skin penetrating carrier (e.g., DMSO with small fractions of water and ethanol), a primary adhesive component (e.g., hydroxypropyl cellulose) to render the anesthetic composition sticky to the persons tissue, and at least one anesthetic component (e.g., -caine based components). Where two anesthetic components are included, one may act more rapidly to anesthetize pain than the first anesthetic component.
