Packhaeuser, Claudia,Steiger, Norbert,Liepold, Bernd,Kostelac, Drazen,Knobloch, Martin
申请号：
AU2010258367
公开号：
AU2010258367A1
申请日:
2010.06.08
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The invention relates to a pharmaceutical dosage form which comprises a solid dispersion product comprising N-(4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-l-cyclohex-l-en- 1-yl)methyl)piperazin- 1-yl)benzoyl)-4-(((1R)-3-(morpholin-4-yl)-1- ((phenylsulfanyl)methyl) propyl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide or a salt, hydrate or solvate thereof, at least one pharmaceutically acceptable polymer, and at least one pharmaceutically acceptable solubilizer. The invention is further directed to processes for preparing the pharmaceutical dosage form and to use of the dosage form for treating proliferative disorders.
