UHLMANN, EUGEN,BREIPOHL, GERHARD,WILL, DAVID WILLIAM
申请号：
CA2406168
公开号：
CA2406168C
申请日:
2001.04.07
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The invention relates to PNA derivatives which carry a phosphoryl radical onthe N terminus of the PNA backbone,for example a phosphate or a substituted phosphoryl radical, substitutedphosphoryl derives optionally carrying one or more markergroups or groups for cross-linking or groups which favor intracellular take-upor groups which increase the binding affinity of thePNA derivative to nucleic acids. The invention also relates to a method forproducing the aforementioned PNA derivatives and totheir use as medicaments and diagnostic agents.
