method for optimizing sensitivity and / or selectivity of a sensor for one or more analytes, method for forming a sensor for one or more analytes, detection kit for one or more analytes, method for identifying an aptamer, composition of matter and aptamers .
Sensors for target entities having functionalized thereon, at least one aptamer specific to the target entity, and methods of making and using the same are described for use in glycated protein monitoring and/or biomarkers.