The present invention provides a medicament for treating an ocular disease comprising a therapeutically effective amount of a cyclohexanehexol compound of the formula III or IV: wherein X is a cyclohexane ring, wherein R 1 , R 2 , R 3 , R 4 , R 5 , and R 6 are hydroxyl or at least one of R 1 , R 2 , R 3 , R 4 , R 5 , and R 6 is independently selected from hydrogen, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 alkoxy, C 2 -C 6 alkenyloxy, C 3 -C 10 cycloalkyl, C 4 -C 10 cycloalkenyl, C 3 -C 10 cycloalkoxy, C 6 -C 10 aryl, C 6 -C 10 aryloxy, C 6 -C 10 aryl-C 1 -C 3 alkoxy, C 6 -C 10 aroyl, C 6 -C 10 heteroaryl, C 3 -C 10 heterocyclic, C 1 -C 6 acyl, C 1 -C 6 acyloxy, -NH 2 , -NHR 7 , -NR 7 R 8 , =NR 7 , -S(O) 2 R 7 , -SH, -SO 3 H, nitro, cyano, halo, haloalkyl, haloalkoxy, hydroxyalkyl, -Si(R 7 ) 3 , -OSi(R 7 ) 3 , -CO 2 H, -CO 2 R 7 , oxo, -PO 3 H, -NHC(O)R 7 , -C(O)NH 2 , -C(O)NHR 7 , -C(O)NR 7 R 8 , -NHS(O) 2 R 7 , -S(O) 2 NH 2 , -S(O) 2 NHR 7 , and -S(O) 2 NR 7 R 8 wherein R 7 and R 8 are independently selected from C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 3 -C 10 cycloalkyl, C 4 -C 10 cycloalkenyl, C 6 -C 10 aryl, C 6 -C 10 aryl C 1 -C 3 alkyl, C 6 -C 10 heteroaryl and C 3 -C 10 heterocyclic, and at least one of the remainder of R 1 , R 2 , R 3 , R 4 , R 5 , or R 6 is hydroxyl； or a pharmaceutically acceptable salt thereof.
