Traditional photodynamic therapy (PDT) is a method of using a visible light with a certain wavelength to irradiate photofrin, converting O 2 into 1 O 2 by energy conversion for treatment of diseases, and many photofrin kinds of new drugs have been marketed and widely used in clinic. The present invention relates to therapeutical mechanism totally different from PDT, in which the specific affinity of photofrin to focus, such as tumors, vascular plaques and skin diseases, is utilized, and a certain means is used to activate photofrin in the focus, catalyze the decomposition reaction of H 2 O 2 to generate 1 O 2 in the focus, 1 O 2 further induces apoptosis and necrosis of cells with pathological changes, the purpose of treating tumors, vascular plaques and skin diseases is achieved, and cosmetic effects on skin are prompted. A series of new drugs obtained via the screening and studying of the present invention are used for Chemodynamic Therapy (CDT), or for Radiochemodynamic Therapy (RCDT) carried out v
