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PEPTIDES INHIBITEURS D`UNE ENZYME DE CONVERSION DE L'ANGIOTENSINE
专利权人:
SUNTORY HOLDINGS LIMITED
发明人:
申请号:
EP04721339.2
公开号:
EP1605969B1
申请日:
2004.03.17
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
It is intended to provide ACE inhibitory tripeptides which are not easily digested by digestive enzymes after being orally taken and thus have fewer tendencies to lose their ACE inhibitory activity in vivo . More specifically, 3 tripeptides having an ACE inhibitory activity and showing a hypotensive effect in an animal experiment are discovered from a thermolysin digestion product of sesame. These tripeptides respectively have amino acid sequences Leu-Ser-Ala, Val-Ile-Tyr and Leu-Val-Tyr and show an angiotensin converting enzyme inhibitory activity.
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