MIRKIN, CHAD A.,THAXTON, C. SHAD,GILJOHANN, DAVID A.,DANIEL, WESTON
申请号：
CA2722183
公开号：
CA2722183C
申请日:
2009.04.24
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Articles, compositions, kits,and methods relating to nanostructures,including those that can sequester moleculessuch as cholesterol, are provided. Certainembodiments described herein include structureshaving a core-shell type arrangement forinstance, a nanoparticle core may be surroundedby a shell including a material, such as a lipidbilayer, that can interact with cholesteroland/or other lipids. In some embodiments, thestructures, when introduced into a subject,can sequester cholesterol and/or other lipidsand remove them from circulation.Accordingly, the structures described herein may beused to diagnose, prevent, treat or managecertain diseases or bodily conditions,especially those associated with abnormal lipidlevels.
