FREISSMUTH MICHAEL,ZEBEDIN BRANDL EVA MARIA,BERGMAYR CHRISTIAN,HUSSAIN FILZA
申请号：
IN6771/DELNP/2013
公开号：
IN2013DN06771A
申请日:
2013.07.30
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
The present invention provides a novel method for enhancing engraftment of haematopoetic stem cells by an ex vivo pretreatment comprising the steps of obtaining a sample containing haematopoetic stem cells and admixing a prostacyclin analogue to obtain a mixture incubating said mixture for a period of time sufficient to stimulate G alphas signalling in said cells and optionally and isolating said stimulated cells. Further a composition comprising a prostacyclin analogue for use in the treatment of individuals undergoing haematopoetic stem cell transplantation is provided.
