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Nucleic acid molecule capable of binding to c-Met and use thereof
专利权人:
Iwao Waga;Naomi Hirabayashi;Shintarou Katou;Shotaro Tsuji;Jou Akitomi;Takashi Ohtsu
发明人:
Naomi Hirabayashi,Shotaro Tsuji,Jou Akitomi,Shintarou Katou,Iwao Waga,Takashi Ohtsu
申请号:
US13812190
公开号:
US08822667B2
申请日:
2011.07.26
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides a nucleic acid molecule capable of binding to c-Met as a substance that can be used for clarification of the pathogenic mechanism of diseases caused by c-Met, diagnosis and treatment of the diseases, and the like, and also the use thereof. The c-Met binding nucleic acid molecule of the present invention is any one of the following nucleic acid molecules (A1), (A2), (B1), and (B2).(A1) a nucleic acid molecule including the base sequence of any one of SEQ ID NOs: 1 to 38(A2) a nucleic acid molecule that is capable of binding to c-Met and includes a base sequence obtained by substitution, deletion, addition, and/or insertion of one or more bases in the base sequence of any one of SEQ ID NOs: 1 to 38(B1) a nucleic acid molecule including the base sequence of any one of SEQ ID NOs: 39 to 76(B2) a nucleic acid molecule that is capable of binding to c-Met and includes a base sequence obtained by substitution, deletion, addition, and/or insertion of one or more bases in the base sequence of any one of SEQ ID NOs: 39 to 76.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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