PDGF FOR USE IN INDUCING PROLIFERATION OF A NEURAL PROGENITOR CELL THAT DIFFERENTIATES INTO NEURONS AND OLIGODENDROCYTES BY NOT ASTROCYTES

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专利权人:

发明人:

申请号：

HK11112607.7

公开号：

HK1158262A

申请日:

2011.11.21

申请国别(地区):

HK

年份:

2012

代理人:

摘要：

The present invention is related to the discovery of a novel class of neural progenitor cells, which proliferate in response to platelet derived growth factor (PDGF) and differentiate into neurons and oligodendrocytes but not astrocytes. Progeny of the progenitor cells can be obtained by culturing brain tissue in PDGF without serum, epidermal growth factor (EGF), fibroblast growth factor 2, or transforming growth factor alpha. Upon subculturing into EGF-containing media, these progeny cells can proliferate and form neurospheres, whereas PDGF has no such effect.

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中国工程科技知识中心

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http://www.ckcest.cn/home/