It relates to a pesticide composition for preventing and controlling fusarium head blight, which contains 1 to 150 parts by weight of jinggangmycin and 1 to 20 parts by weight of metconazole per mu. The pesticide composition of the present invention has an obvious synergistic effect when used for preventing and controlling fusarium head blight, and can remarkably enhance the effect of preventing and controlling head blight, increasing the ability of the human being in preventing and controlling head blight of triticeae crops.