Humanized anti-trop-2 monoclonal antibodies and uses thereof

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专利权人:

ABRUZZO THERANOSTIC S.R.L.

发明人:

Emanuela Guerra,Saverio Alberti

申请号：

US15532598

公开号：

US10501555B2

申请日:

2015.12.04

申请国别(地区):

US

年份:

2019

代理人:

摘要：

The present invention refers to humanized anti-Trop-2 antibodies and their fragments, derivatives and conjugates that are able to recognise and bind with high affinity distinct regions of the Trop-2 molecule. The present invention also teaches the use of such antibodies and of pharmaceutical compositions thereof for diagnosis and therapy of human pathologies, in particular cancer.

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中国工程科技知识中心

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http://www.ckcest.cn/home/