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VACCIN CONTRE LE CLOSTRIDIUM DIFFICILE
专利权人:
NATIONAL RESEARCH COUNCIL OF CANADA (NRC)
发明人:
LOGAN, SUSAN M.,TWINE, SUSAN M.,AUBRY, ANNIE,FULTON, KELLY
申请号:
CA2890580
公开号:
CA2890580A1
申请日:
2015.05.08
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
There are provided compositions and methods for prevention or treatment ofClostridium difficileinfection. More specifically, there are provided Clostridium difficile BcIA3spore glycoproteins, aswell as glycopeptides and glycans thereof, and their use as a vaccine againstClostridiumdifficile. Methods of inducing im munity against Clostridium difficilecomprising administering avaccine or an antibody directed against a Clostridium difficile BcIA3 sporeglycoprotein, orglycopeptide or glycan thereof, are also described.
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