New pyridin-2(1H)-one derivatives having the chemical structure of formula (I) are disclosed as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).Linvention concerne de nouveaux dérivés de pyridin-2(1H)-one ayant la structure chimique de formule (I) ainsi que leur procédé de préparation, des compositions pharmaceutiques les comprenant et leur utilisation en thérapie en tant quinhibiteurs de Janus Kinases (JAK).