Sulfonylated 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine compounds and their use as pharmaceuticals

• 收藏
• 分享

专利权人:

Sabine Hees;Ruth Jostock;Michael Engels;Stefan Oberboersch;Tieno Germann;Beatrix Merla;Melanie Reich;Stefan Schunk;Edward Bijsterveld

发明人:

Beatrix Merla,Stefan Oberboersch,Melanie Reich,Stefan Schunk,Ruth Jostock,Sabine Hees,Michael Engels,Tieno Germann,Edward Bijsterveld

申请号：

US12717625

公开号：

US08158628B2

申请日:

2010.03.04

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Sulfonylated tetrahydroazolopyrazine compounds corresponding to the formula Iwherein R1, R2a, R2b, R3a, R3b, R4, R8, R9a, R9b, R10, R11, A, B, W1, W2 and W3 have the meanings defined herein, pharmaceutical compositions containing such compounds, a method for the preparation of such compounds, and the use of such compounds for treating or inhibiting various types of pain and/or other conditions mediated at least in part by the bradykinin 1 receptor (B1R).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/