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SYSTEM AND METHOD FOR THE RELEASE OF NITRIC OXIDE USING NANOSCALE MEDIA
专利权人:
SYRACUSE UNIVERSITY
发明人:
MATHER, PATRICK,ONYEJEKWE, IFEANYI,ISHIDA, KAZUKI
申请号:
EP11766664
公开号:
EP2555762A4
申请日:
2011.04.06
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
A composite material containing polymeric nanofibers, themselves containing NO-donor molecules, imbibed with an elastomer matrix is permeable to both water and gas so that dissociation reactions in the presence of water releases NO gas in a sustained manner. The NO-donor nanofibers may be formed by synthesizing acceptable NO-donor molecules, blending such molecules in solution with PVP, PCL or PVAc, electrospinning the blend at relatively high voltage for form fiber mats, applying PDMS rubber to the fiber mat and crosslinking it. The resulting NO-releasing electrospun fiber composite may be used in medical devices such as catheters, stents, or vascular grafts, with the purpose of releasing nitric oxide within a controlled rate and for a sustained period of time, as well as other known medical applications for NO.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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