ФАТХИ Реза (US),МАКЛИН Патрик Лафлин (CA),ЛЕЙТОН Гарри Джефферсон (US)
申请号：
RU2014115807/15
公开号：
RU2014115807A
申请日:
2012.09.19
申请国别(地区):
RU
年份:
2015
代理人:
摘要：
1. A composition comprising an effective amount of rifabutin, an effective amount of clarithromycin and an effective amount of clofazimine, in which effective amounts of rifabutin, clarithromycin and clofazimine are sufficient to provide treatment for a subject having an autoimmune disease by targeting cytokines or cytokine receptors. 2. The composition according to claim 1, additionally containing an antibiotic selected from the group consisting of daptomycin, clindamycin, rifampicin, erythromycin, oleandomycin, roxithromycin, azithromycin, kanamycin, gentamicin, tobramycin, streptomycin, neomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycin, etomycemin 3. The composition of claim 1, wherein the autoimmune disease is a disease of the central nervous system. The composition of claim 1, wherein the autoimmune disease is multiple sclerosis. The composition of claim 1, wherein the autoimmune disease is Hashimoto's thyroiditis, Melkerssson-Rosenthal syndrome, or sarcoidosis. The composition according to claim 1, formulated for oral administration. The composition according to claim 1, formulated for intravenous administration. The composition of claim 1, wherein clofazimine is dispersed into a absorption enhancer. The composition of claim 8, in which the absorption enhancer is a polyethylene glycol. 10. The composition of claim 1, further comprising an anti-inflammatory agent selected from one of these substances or from a combination of 5-aminosalicylic acid, azathioprine, or methotrexate. A method for treating a subject having an autoimmune disease, c
