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Polysaccharide-staphylococcal surface adhesin carrier protein conjugates for immunization against nosocomial infections
专利权人:
Viliam Pavliak
发明人:
Viliam Pavliak,Steven Morris Baker,Subramonia Padmanaba Pillai,Joseph M. Patti,Bradley D. Prater
申请号:
US11593481
公开号:
US08377451B2
申请日:
2006.11.07
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Immunogenic polysaccharide-protein conjugates having a polysaccharide antigen (or its oligosaccharide fragment representing one or more antigenic epitopes) derived from a nosocomial pathogen conjugated to a staphylococcal surface adhesin carrier protein are used in immunogenic compositions to elicit antibody responses to both the polysaccharide antigen and the staphylococcal surface adhesin carrier protein. Such immunogenic compositions are used to immunize against diseases caused by Staphylococcal aureus, Staphylococcal epidermidis or other nosocomial pathogens.
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